Signature ECG part 5: Exercise induced syncope
14-year-old boy presented with aborted sudden cardiac arrest during exertion. His brother died suddenly at 16 years of age during an emotional situation. On stress testing, patient developed classical bidirectional PVCs typical of CPVT (Catecholaminergic polymorphic ventricular tachycardia). The genetic testing showed pathogenic heterozygous variant in CASQ<sub>2</sub> gene. Patient was started on propranolol and flecainide and advised to avoid strenuous physical activity.
Authors
- Anand Manickavasagam (ORCID: https://orcid.org/0000-0002-9435-8067)
- Arthur A M Wilde
Institutions
- Christian Medical College, Vellore (IN)
- Christian Medical College (IN)
- Amsterdam University Medical Centers (NL)
- University of Amsterdam (NL)
Publication Details
- Journal
- Indian Pacing and Electrophysiology Journal
- Published
- 2025-11-25
- DOI
- https://doi.org/10.1016/j.ipej.2025.11.010
- Citations
- 1
- Primary Topic
- Cardiac electrophysiology and arrhythmias
- Type
- article
- Field-Weighted Citation Impact
- 1.39