Intrauterine Devices and Risk of Ectopic Pregnancy

In this nationwide cohort study comparing three doses of hormonal IUDs and copper IUDs, the highest dose (levonorgestrel 52 mg) was associated with the lowest risk of ectopic pregnancy within 1 year compared with copper IUDs, whereas the 13.5-mg hormonal IUD was associated with the highest risk. (Funded by the French National Fund for Health Insurance and the French National Agency for Medicines and Health Products Safety.).

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Publication Details

Journal
NEJM Evidence
Published
2025-11-25
DOI
https://doi.org/10.1056/evidoa2500117
Citations
2
Primary Topic
Ectopic Pregnancy Diagnosis and Management
Type
article
Field-Weighted Citation Impact
3.76
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article

Intrauterine Devices and Risk of Ectopic Pregnancy

Pauline Dayani, Lorraine Poncet, Rosemary Dray‐Spira, Epiphane Kolla et al.
2 citations
NEJM Evidence
Ectopic Pregnancy Diagnosis and Management
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article

Intrauterine Devices and Risk of Ectopic Pregnancy

Pauline Dayani, Lorraine Poncet, Rosemary Dray‐Spira, Epiphane Kolla, Mahmoud Zureik, Lise Duranteau, Noémie Roland, Alain Weill
article en
2 citations

Abstract

In this nationwide cohort study comparing three doses of hormonal IUDs and copper IUDs, the highest dose (levonorgestrel 52 mg) was associated with the lowest risk of ectopic pregnancy within 1 year compared with copper IUDs, whereas the 13.5-mg hormonal IUD was associated with the highest risk. (Funded by the French National Fund for Health Insurance and the French National Agency for Medicines and Health Products Safety.).

NEJM EvidenceVol. 4(12)
Université de Versailles Saint-Quentin-en-Yvelines (FR), Université Paris-Saclay (FR), Bicêtre Hospital (FR)
Openalex Percentile: Top 6%
Ectopic Pregnancy Diagnosis and Management
3.76
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