Ferroptosis and cancer: when iron turns against tumors
Ferroptosis functions both as an intrinsic tumor-suppressive mechanism and a tractable therapeutic vulnerability. Harnessing ferroptosis offers a promising strategy for targeting iron-addicted cancers.
Authors
- Yingyi Kong (ORCID: https://orcid.org/0000-0002-6481-0745)
- Hiromasa Tanaka (ORCID: https://orcid.org/0000-0003-0105-6017)
- Yashiro Motooka (ORCID: https://orcid.org/0000-0002-4230-7559)
- Yuuki Ohara (ORCID: https://orcid.org/0000-0002-9171-4724)
- Qinying Lyu
- Kotaro Sato (ORCID: https://orcid.org/0000-0002-8442-5318)
- Shinya Toyokuni (ORCID: https://orcid.org/0000-0002-5757-1109)
- Kae Nakamura (ORCID: https://orcid.org/0000-0002-0709-4738)
- Yuki K. Maeda (ORCID: https://orcid.org/0000-0001-6460-029X)
Institutions
- National Institute for Fusion Science (JP)
- Nagoya University (JP)
Publication Details
- Journal
- Cellular and Molecular Life Sciences
- Published
- 2025-11-25
- DOI
- https://doi.org/10.1007/s00018-025-05982-5
- Primary Topic
- Ferroptosis and cancer prognosis
- Type
- article
- Field-Weighted Citation Impact
- 0.00