Mesenchymal stem/stromal cells overexpressing leukemia inhibitory factor (LIF) promote arteriogenesis and functional recovery in a mouse model of critical hindlimb ischemia
LIF overexpression is a promising strategy to increase the potential of MSC in the treatment of CLI and for tissue repair.
Authors
- Tiago O. Ribeiro (ORCID: https://orcid.org/0000-0002-9589-7986)
- Milena Botelho Pereira Soares (ORCID: https://orcid.org/0000-0001-7549-2992)
- Rosane B. Dias (ORCID: https://orcid.org/0000-0002-9491-334X)
- Rosalia Méndez‐Otero (ORCID: https://orcid.org/0000-0002-1798-9930)
- Vitor Fortuna
- Carine Machado Azevedo
- Mariá C. V. Nascimento (ORCID: https://orcid.org/0000-0002-3094-6847)
- Ivanilson Pimenta Santos (ORCID: https://orcid.org/0000-0002-2331-6150)
- Daniela Nascimento Silva (ORCID: https://orcid.org/0000-0003-2165-4989)
- Beatriz Costa
- Girlaine Café Santos
Institutions
- Universidade Federal do Rio de Janeiro (BR)
- Universidade Federal da Bahia (BR)
- Instituto Federal da Bahia (BR)
- Serviço Nacional de Aprendizagem Industrial (BR)
- Universidade Estadual de Feira de Santana (BR)
- Karolinska Institutet (SE)
- Fundação Oswaldo Cruz (BR)
Publication Details
- Journal
- Stem Cell Research & Therapy
- Published
- 2025-11-25
- DOI
- https://doi.org/10.1186/s13287-025-04762-z
- Primary Topic
- Cytokine Signaling Pathways and Interactions
- Type
- article
- Field-Weighted Citation Impact
- 0.00