Integrative bioinformatics and machine learning approaches identify inflammation-related genes and drug candidates for future preclinical validation in ischemic stroke
This study reveals four inflammation-related genes with preliminary diagnostic value and proposes capecitabine and ruxolitinib as candidate drugs for future preclinical research on IS.
Authors
- Xiaoli Huang (ORCID: https://orcid.org/0000-0002-2833-3523)
- Weidong Han (ORCID: https://orcid.org/0000-0003-3207-3899)
- Jialu Yuan
- Haiyang Fu
Institutions
- Harbin Medical University (CN)
- Nantong University (CN)
- Affiliated Hospital of Nantong University (CN)
- People's Hospital of Shiyan (CN)
Publication Details
- Journal
- BMC Neurology
- Published
- 2025-11-25
- DOI
- https://doi.org/10.1186/s12883-025-04525-6
- Primary Topic
- Neuroinflammation and Neurodegeneration Mechanisms
- Type
- article
- Field-Weighted Citation Impact
- 0.00