Identification and validation of PANoptosis-related biomarkers in Alzheimer’s disease via single-cell RNA sequencing and machine learning
This study identified five novel PANoptosis-related biomarkers with diagnostic and therapeutic potential in AD. These findings provide a theoretical basis for future clinical research and may contribute to improved AD diagnosis and treatment strategies.
Authors
- L. J. Li
- Fangfang Xu (ORCID: https://orcid.org/0000-0003-1364-7930)
- Junjia Qi
- Kai Ma (ORCID: https://orcid.org/0000-0003-4415-6894)
- Hongyan Duan (ORCID: https://orcid.org/0009-0007-7884-5950)
- Jingyi Zhang (ORCID: https://orcid.org/0009-0006-5588-4642)
Institutions
- Zhengzhou University (CN)
- Henan Provincial People's Hospital (CN)
- Zhengzhou People's Hospital (CN)
Publication Details
- Journal
- European journal of medical research
- Published
- 2025-11-25
- DOI
- https://doi.org/10.1186/s40001-025-03335-3
- Primary Topic
- Single-cell and spatial transcriptomics
- Type
- article
- Field-Weighted Citation Impact
- 0.00