Hypolipidemic, anti-inflammatory, and neurotrophic effects of a multicomponent nutraceutical containing berberine, bergamot, and amaranth in mild-to-moderate hypercholesterolemia.
This nutraceutical formulation effectively and safely reduced TC and LDL-C in low-risk subjects with mild hypercholesterolemia. The twice-daily regimen provided superior lipid improvements and increased HDL-C and BDNF levels, indicating additional antioxidant, anti-inflammatory, and neuroprotective properties warranting further investigation.
Authors
- Paula Crespo‐Escobar (ORCID: https://orcid.org/0000-0003-3180-9024)
- Kayvan Khoramipour (ORCID: https://orcid.org/0000-0003-1598-8640)
- Simone Lista (ORCID: https://orcid.org/0000-0001-6804-7858)
- Piercarlo Minoretti (ORCID: https://orcid.org/0000-0002-6512-611X)
- Alejandro Santos‐Lozano (ORCID: https://orcid.org/0000-0002-2309-3583)
- Enzo Emanuele (ORCID: https://orcid.org/0000-0003-3908-0290)
Institutions
- Universidad Europea Miguel de Cervantes (ES)
- Research Institute Hospital 12 de Octubre (ES)
Publication Details
- Journal
- PubMed
- Published
- 2025-11-04
- Primary Topic
- Berberine and alkaloids research
- Type
- article
- Field-Weighted Citation Impact
- 0.00