Association of preoperative chronic opioid use with 1-year revision rate, mortality, and patient-reported outcomes after primary hip and knee arthroplasty: age, sex and BMI matter – a Dutch register-based study

Preoperative chronic opioid use was associated with a higher likelihood of 1-year revision and mortality and worse PROs. The associations with revision risk were modified by age, sex, and BMI. Age also had a modifying effect on PROs.

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Publication Details

Journal
Acta Orthopaedica
Published
2025-11-22
DOI
https://doi.org/10.2340/17453674.2025.44597
Primary Topic
Opioid Use Disorder Treatment
Type
article
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article

Association of preoperative chronic opioid use with 1-year revision rate, mortality, and patient-reported outcomes after primary hip and knee arthroplasty: age, sex and BMI matter – a Dutch register-based study

Marcel L. Bouvy, Heather E. van Brug, Liza N. van Steenbergen, Rob G. H. H. Nelissen et al.
Acta Orthopaedica
Opioid Use Disorder Treatment
article

Association of preoperative chronic opioid use with 1-year revision rate, mortality, and patient-reported outcomes after primary hip and knee arthroplasty: age, sex and BMI matter – a Dutch register-based study

Marcel L. Bouvy, Heather E. van Brug, Liza N. van Steenbergen, Rob G. H. H. Nelissen, Maaike G. J. Gademan, Albert Dahan, F.R. Rosendaal
article en

Abstract

Preoperative chronic opioid use was associated with a higher likelihood of 1-year revision and mortality and worse PROs. The associations with revision risk were modified by age, sex, and BMI. Age also had a modifying effect on PROs.

Acta OrthopaedicaVol. 96
Utrecht University (NL), Leiden University Medical Center (NL), Netherlands Heart Registration (NL)
Openalex Percentile: Top 53%
Opioid Use Disorder Treatment
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