Characteristics of indeterminate QuantiFERON-TB Gold PLUS results in pediatric lupus nephritis at Beijing Children’s Hospital, 2023–2024

Hospitalized patients with LN had a high rate of an indeterminate QFT-Plus result, predominantly in positive control failure. Besides, our data showed that the use of immunotherapy agents and high triglycerides level represent factors associated with indeterminate QFT-Plus results in our cohort of pediatric lupus nephritis patients.

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Publication Details

Journal
BMC Nephrology
Published
2025-11-25
DOI
https://doi.org/10.1186/s12882-025-04652-9
Primary Topic
Systemic Lupus Erythematosus Research
Type
article
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article

Characteristics of indeterminate QuantiFERON-TB Gold PLUS results in pediatric lupus nephritis at Beijing Children’s Hospital, 2023–2024

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Characteristics of indeterminate QuantiFERON-TB Gold PLUS results in pediatric lupus nephritis at Beijing Children’s Hospital, 2023–2024

Fei-Na Li, Jing Xiao, Yonghong Wang, Zhi Chen, Yajie Guo, Huiwen Zheng, Yue Xi, Lin Sun, Nathalie Zhou, Hui Qi, Weiwei Jiao
article en

Abstract

Hospitalized patients with LN had a high rate of an indeterminate QFT-Plus result, predominantly in positive control failure. Besides, our data showed that the use of immunotherapy agents and high triglycerides level represent factors associated with indeterminate QFT-Plus results in our cohort of pediatric lupus nephritis patients.

BMC NephrologyVol. 27(1)
Capital Medical University (CN), Beijing Children’s Hospital (CN)
Openalex Percentile: Top 49%
Systemic Lupus Erythematosus Research
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