Advancements in metastatic spinal cord compression treatment: a narrative review of innovations, challenges, and future directions
Prompt, multimodal treatment is necessary, including corticosteroids, surgery, and radiation therapy to reduce symptoms and enhance patient outcomes. Despite advancements, challenges such as delayed diagnosis and limited access to specialized treatments persist. Precision medicine, artificial intelligence-based diagnostics, and easier access to clinical trials should be the main areas of future development. Preventing irreparable neurological impairments and improving patient quality of life requires a focus on palliative care and early intervention. Integrating innovative therapies with comprehensive supportive care in a patient-centered study is essential for enhancing neurological function, pain control, and overall quality of life.
Authors
- Anthony Noor (ORCID: https://orcid.org/0000-0003-1792-0834)
- Iman Sharif
- Muhammad R. Ishaque
- Tirath Patel
- Nikhilesh Anand (ORCID: https://orcid.org/0000-0002-2986-3550)
- Hafiza Tooba Siddiqui (ORCID: https://orcid.org/0009-0008-7506-2886)
- Niloufer Khan (ORCID: https://orcid.org/0000-0002-8631-5710)
- Christopher Hanani
- Abhishek Goyal
- Zarhaish Barkatullah
- Fathimathul Henna
Institutions
- Khyber Medical College (PK)
- Henry Ford Health System (US)
- Trinity School of Medicine (VC)
- Jinnah Sindh Medical University (PK)
- The University of Texas Rio Grande Valley (US)
- University Medical Center (US)
- Farooq Hospital (PK)
- Dow University of Health Sciences (PK)
- University Hospital and Clinics (US)
- Dubai Medical College (AE)
- John F. Kennedy Medical Center (US)
Publication Details
- Journal
- Annals of Medicine and Surgery
- Published
- 2025-11-25
- DOI
- https://doi.org/10.1097/ms9.0000000000004382
- Primary Topic
- Management of metastatic bone disease
- Type
- article
- Field-Weighted Citation Impact
- 0.00