Cerebral microstructural alteration patterns in motor subtypes of Parkinson’s disease: a neurite orientation dispersion and density imaging study
PIGD exhibited more extensive cerebral microstructural alterations than TD, and the microstructures showed significant cognitive correlations. NODDI-derived metrics may serve as potential biomarkers for cognitive and motor symptom assessment in PD.
Authors
- Junqiao Wang (ORCID: https://orcid.org/0000-0001-5490-6842)
- Chen Zhao (ORCID: https://orcid.org/0000-0002-3952-3859)
- Yingqian Huang
- Jianping Chu (ORCID: https://orcid.org/0000-0001-5483-2169)
- Zhiyun Yang (ORCID: https://orcid.org/0000-0002-6139-9049)
- Zihuan Huang
- Siyuan He (ORCID: https://orcid.org/0000-0003-3698-6724)
- Nengjin Zhu
- Nan Jiang (ORCID: https://orcid.org/0000-0001-8970-6090)
- Changming Zhang (ORCID: https://orcid.org/0000-0002-2869-6180)
- Jing Zhao (ORCID: https://orcid.org/0000-0001-9464-0735)
- Yuting Ling (ORCID: https://orcid.org/0000-0002-6097-6692)
- Jianmin Chu (ORCID: https://orcid.org/0009-0003-1489-1318)
- Ling Chen (ORCID: https://orcid.org/0000-0002-6909-9606)
Institutions
- Sun Yat-sen University (CN)
- The First Affiliated Hospital, Sun Yat-sen University (CN)
- Siemens (China) (CN)
Publication Details
- Journal
- Quantitative Imaging in Medicine and Surgery
- Published
- 2025-11-25
- DOI
- https://doi.org/10.21037/qims-2025-34
- Citations
- 1
- Primary Topic
- Parkinson's Disease Mechanisms and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 1.39