Disrupted intrinsic functional brain topology in patients with basal ganglia ischemic stroke

This study identified a BGIS-induced reconfiguration of brain network topology, characterized by a tendency toward randomization, compensatory hyperconnectivity in motor regions, and impaired integration in cognitive networks. The findings indicated the right precentral gyrus to be a pivotal hub for poststroke recovery and offers novel insights into network-level mechanisms and potential targets for neuromodulatory interventions.

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Publication Details

Journal
Quantitative Imaging in Medicine and Surgery
Published
2025-11-25
DOI
https://doi.org/10.21037/qims-2025-317
Primary Topic
Functional Brain Connectivity Studies
Type
article
Field-Weighted Citation Impact
0.00
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article

Disrupted intrinsic functional brain topology in patients with basal ganglia ischemic stroke

Liang Huo, Qian Yang, Shijian Chen, Xuemei Quan et al.
Quantitative Imaging in Medicine and Surgery
Functional Brain Connectivity Studies
article

Disrupted intrinsic functional brain topology in patients with basal ganglia ischemic stroke

Liang Huo, Qian Yang, Shijian Chen, Xuemei Quan, Yayuan Liu, Zhijian Liang, Jian Zhang
article en

Abstract

This study identified a BGIS-induced reconfiguration of brain network topology, characterized by a tendency toward randomization, compensatory hyperconnectivity in motor regions, and impaired integration in cognitive networks. The findings indicated the right precentral gyrus to be a pivotal hub for poststroke recovery and offers novel insights into network-level mechanisms and potential targets for neuromodulatory interventions.

Quantitative Imaging in Medicine and SurgeryVol. 15(12)
Guangxi Medical University (CN), The People's Hospital of Guangxi Zhuang Autonomous Region (CN), First Affiliated Hospital of GuangXi Medical University (CN), Affiliated Hospital of Youjiang Medical University for Nationalities (CN), Fourth Affiliated Hospital of Guangxi Medical University (CN), Guangxi Center for Disease Prevention and Control (CN)
Openalex Percentile: Top 64%
Functional Brain Connectivity Studies
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Disrupted intrinsic functional brain topology in patients with basal ganglia ischemic stroke — Liang Huo, Qian Yang, et al. · Quantitative Imaging in Medicine and Surgery (2025) | TGRS Research Map | TGRS