Regioselective functionalization of sulfenamides: <i>S</i> -arylation with cyclic diaryl λ <sup>3</sup> -bromanes and λ <sup>3</sup> -chloranes
We report an <i>S</i>-selective and <i>meta</i>-regioselective arylation of sulfenamides with cyclic diaryl λ<sup>3</sup>-bromanes and λ<sup>3</sup>-chloranes. This metal-free strategy proceeds under mild conditions, tolerates diverse functional groups, and delivers <i>S</i>-aryl sulfilimines in good to excellent yields with high regioselectivity. The method is scalable, enabling scale-up synthesis and further transformations, highlighting the potential for efficient late-stage functionalization.
Authors
- Xiaoping Xu (ORCID: https://orcid.org/0000-0001-8031-3688)
- Weichun Huang (ORCID: https://orcid.org/0000-0002-1948-8347)
- Xin‐Xing Wu (ORCID: https://orcid.org/0000-0001-9384-0006)
- You Zi (ORCID: https://orcid.org/0000-0002-6960-2646)
- Yuan‐Yuan Huang (ORCID: https://orcid.org/0000-0002-0775-9197)
- Nan Wang (ORCID: https://orcid.org/0000-0003-2796-3977)
- Jiahong Chen (ORCID: https://orcid.org/0000-0002-2905-4673)
- Mengke Wang (ORCID: https://orcid.org/0000-0002-4521-194X)
Institutions
- Nantong University (CN)
- Soochow University (CN)
Publication Details
- Journal
- Chemical Communications
- Published
- 2025-11-25
- DOI
- https://doi.org/10.1039/d5cc05327g
- Citations
- 1
- Primary Topic
- Sulfur-Based Synthesis Techniques
- Type
- article
- Field-Weighted Citation Impact
- 0.94