Fluorescence monitoring of STING using a coumarin-based chemigenetic probe
Protein condensates are critical to cell fate decisions and cellular homeostasis. Here, we report a de novo design strategy for a coumarin-based chemigenetic probe that enables precise monitoring of STING protein dynamics in living cells.
Authors
- Andong Shao
- Xuekun Zhang
- Yongping Li (ORCID: https://orcid.org/0000-0002-3253-4088)
- Yu Jiang (ORCID: https://orcid.org/0009-0003-4071-9239)
- Haozhou Tang
- Jianming Ni
- Ying Wang (ORCID: https://orcid.org/0000-0001-6638-8026)
Institutions
- Jiangnan University (CN)
- Soochow University (CN)
- Wuxi Ninth People's Hospital (CN)
- Wuxi People's Hospital (CN)
Publication Details
- Journal
- New Journal of Chemistry
- Published
- 2025-11-25
- DOI
- https://doi.org/10.1039/d5nj03804a
- Primary Topic
- interferon and immune responses
- Type
- article
- Field-Weighted Citation Impact
- 0.00