Quantitative [18F]FDOPA PET/CT for the characterization of biochemical phenotypes in paraganglioma and pheochromocytoma
Radioligand uptake on [<sup>18</sup>F ]FDOPA PET/CT is associated with the biochemical phenotype of PPGL. This finding may facilitate the metabolic profiling of patients with suspected impaired or delayed laboratory results. Normetanephrine concentrations in plasma and 24-hour urine may be employed as predictive markers of MTV and TLU.
Authors
- Ulrike Disko
- Martín Reincke (ORCID: https://orcid.org/0000-0002-9817-9875)
- Christoph Josef Auernhammer (ORCID: https://orcid.org/0000-0001-8087-3722)
- Júnia Ribeiro de Oliveira Longo Schweizer (ORCID: https://orcid.org/0000-0002-8050-9127)
- Christine Schmid‐Tannwald (ORCID: https://orcid.org/0000-0002-7304-6961)
- Christian Lottspeich (ORCID: https://orcid.org/0000-0002-1770-4392)
- Rudolf Alexander Werner (ORCID: https://orcid.org/0000-0003-3372-6046)
- Alessa Fischer (ORCID: https://orcid.org/0000-0003-4555-8334)
- Matthias Kroiß (ORCID: https://orcid.org/0000-0002-7628-3161)
- Friederike Völter (ORCID: https://orcid.org/0000-0001-6157-0363)
- Isabel Stüfchen (ORCID: https://orcid.org/0009-0007-6846-6893)
- Katharina Wang (ORCID: https://orcid.org/0000-0002-7795-1395)
- Martin Bidlingmaier (ORCID: https://orcid.org/0000-0002-4681-6668)
- Nabeel Mansour (ORCID: https://orcid.org/0000-0002-3467-1916)
- Matthias Brendel (ORCID: https://orcid.org/0000-0002-6522-4895)
- Matthias K. Auer (ORCID: https://orcid.org/0000-0001-7153-8332)
- Svenja Nölting (ORCID: https://orcid.org/0000-0002-7064-590X)
- Meike Onkes
- Paul Dahlmann
- Sophie C. Kunte (ORCID: https://orcid.org/0009-0003-3175-952X)
Institutions
- Johns Hopkins University (US)
- Johns Hopkins Medicine (US)
- LMU Klinikum (DE)
- University Hospital of Zurich (CH)
- Ludwig-Maximilians-Universität München (DE)
Publication Details
- Journal
- EJNMMI Reports
- Published
- 2025-11-23
- DOI
- https://doi.org/10.1186/s41824-025-00275-3
- Citations
- 1
- Primary Topic
- Adrenal and Paraganglionic Tumors
- Type
- article
- Field-Weighted Citation Impact
- 2.01