Polycystic Disease of the Salivary Glands: A Rare Cause of Bilateral Parotid Enlargement

Non-neoplastic cysts are rare, causing salivary gland enlargement. Among these, one of the rarest entities is dysgenetic polycystic disease (DPD) of the salivary glands. Also referred to simply as polycystic disease, DPD is a rare developmental anomaly of the salivary gland ductal system, characterized by distinctive histopathological features. It is an uncommon cause of parotid gland enlargement, with only 22 cases documented in the literature to date. We present a case of DPD in a female patient who exhibited bilateral enlargement of the parotid glands. The diagnosis was confirmed using magnetic resonance imaging (MRI), and the patient was referred to a surgeon who opted for a total parotidectomy.