Association between triglyceride glucose-body mass index and long-term adverse outcomes in individuals with heart failure: a retrospective cohort study

A U-shaped association was observed: both very low and very high TyG-BMI were associated with increased all-cause mortality and HF rehospitalization. These findings support the potential utility of TyG-BMI as a prognostic biomarker for risk stratification. Furthermore, TyG-BMI appears to modify the relationship between RVD and adverse clinical outcomes, with obesity potentially exerting a modulatory effect.