Revealing the genetic basis of coat color in Tibetan sheep through selective sweep and transcriptomic analyses
Two molecular markers (rs3508196008 and rs409651063) in the <i>MC1R</i> gene regulating Tibetan coat color were identified through selective sweep analysis, transcriptome, Sanger sequencing, and the genetic mechanism of coat color was analyzed, which provided new insights for the genetics of coat color in Tibetan sheep, and provided effective markers and technical support for molecular breeding.
Authors
- Buying Han (ORCID: https://orcid.org/0000-0001-8621-0700)
- Quanbang Pei (ORCID: https://orcid.org/0000-0003-0244-0643)
- Zian Zhang (ORCID: https://orcid.org/0009-0005-7999-2640)
- Wentai Ma (ORCID: https://orcid.org/0000-0003-1931-8687)
- Dehui Liu (ORCID: https://orcid.org/0000-0002-8677-022X)
- Guolian Bao (ORCID: https://orcid.org/0000-0001-8327-9921)
- Dehong Tian (ORCID: https://orcid.org/0000-0003-2103-8123)
- Xue Li (ORCID: https://orcid.org/0000-0002-6969-0674)
- Kai Zhao (ORCID: https://orcid.org/0000-0002-4693-7611)
- Lei Wang (ORCID: https://orcid.org/0000-0003-0734-7026)
Institutions
- Qinghai University (CN)
- Chinese Academy of Sciences (CN)
- Xinjiang Institute of Ecology and Geography (CN)
- Ningxia Water Conservancy (CN)
- Qinghai Provincial Peoples Hospital (CN)
- University of Chinese Academy of Sciences (CN)
Publication Details
- Journal
- Frontiers in Veterinary Science
- Published
- 2025-11-24
- DOI
- https://doi.org/10.3389/fvets.2025.1711294
- Primary Topic
- melanin and skin pigmentation
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Natural Science Foundation of Qinghai