Dietary curcumin alleviates aflatoxin <scp> B <sub>1</sub> </scp> ‐induced liver injury and improves growth performance in broilers via Nrf2 activation and <scp>NLRP3</scp> inflammasome inhibition
Dietary curcumin effectively mitigated AFB<sub>1</sub>-induced hepatotoxicity and performance loss in broilers through activation of the Nrf2 antioxidant pathway and inhibition of the NLRP3 inflammasome. These findings highlight CUR as a promising natural feed additive for protecting poultry against mycotoxin-induced oxidative and inflammatory damage. © 2025 Society of Chemical Industry.
Authors
- Zesheng Yin
- Ruoshi Zhang (ORCID: https://orcid.org/0000-0003-0508-1498)
- Xingjun Feng (ORCID: https://orcid.org/0000-0001-6809-5913)
- Han Chen (ORCID: https://orcid.org/0000-0001-8637-4289)
- Xinyu Wang (ORCID: https://orcid.org/0000-0002-9169-1710)
- Yu Hao (ORCID: https://orcid.org/0009-0004-0906-8172)
- Shenao Wang (ORCID: https://orcid.org/0000-0002-0668-9107)
Institutions
- Northeast Agricultural University (CN)
Publication Details
- Journal
- Journal of the Science of Food and Agriculture
- Published
- 2025-11-23
- DOI
- https://doi.org/10.1002/jsfa.70337
- Primary Topic
- Curcumin's Biomedical Applications
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Natural Science Foundation of China