The regulatory effects of realgar and cinnabar on glucose metabolism in mice
This study provides the first systematic evidence that realgar and cinnabar exert hypoglycemic effects, which involving enhanced insulin secretion and inhibition of key digestive enzymes. Their substrate-specific actions and partial influence on thermoregulation suggest broader roles in metabolic regulation and warrant further investigation in chronic models and energy homeostasis pathways.
Authors
- Ruiyan Liu (ORCID: https://orcid.org/0000-0001-5456-0423)
- Qingsong Qu (ORCID: https://orcid.org/0000-0002-0190-7187)
- Yan Zhao (ORCID: https://orcid.org/0000-0002-4336-0028)
- Hui Kong (ORCID: https://orcid.org/0000-0002-1382-7985)
- Bao Sheng Jin
- Yifan Zhang (ORCID: https://orcid.org/0000-0002-6573-1512)
- Zixuan Lu (ORCID: https://orcid.org/0009-0001-4550-2296)
- Huihua Qu
- Ertong Dai
Institutions
- Beijing University of Chinese Medicine (CN)
Publication Details
- Journal
- Frontiers in Endocrinology
- Published
- 2025-11-24
- DOI
- https://doi.org/10.3389/fendo.2025.1658148
- Primary Topic
- Natural Antidiabetic Agents Studies
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Fundamental Research Funds for the Central Universities