Drug-induced polycystic ovary syndrome: a real-world pharmacovigilance study based on the FAERS database
This study is the first large-scale, systematic exploration of drug signals related to PCOS using the FAERS database. The drugs identified are primarily associated with the nervous system, followed by respiratory system medications and other types of drugs. These findings provide new warning evidence and references for clinical drug safety, suggesting that enhanced monitoring of female patients should be implemented when prescribing such drugs.
Authors
- Zhuo Zhou (ORCID: https://orcid.org/0000-0001-5862-9854)
- Yanqiang Gou (ORCID: https://orcid.org/0000-0002-8726-3940)
- Man Di (ORCID: https://orcid.org/0000-0001-7789-387X)
- Yu Wang
- Huiping Zhang (ORCID: https://orcid.org/0000-0002-4902-0104)
- Yingying Ma (ORCID: https://orcid.org/0000-0003-4004-6890)
Institutions
- Northwest University (CN)
- Yan'an University (CN)
- Tang Du Hospital (CN)
- First Hospital of Xi'an (CN)
Publication Details
- Journal
- Frontiers in Endocrinology
- Published
- 2025-11-24
- DOI
- https://doi.org/10.3389/fendo.2025.1671511
- Primary Topic
- Pharmacovigilance and Adverse Drug Reactions
- Type
- article
- Field-Weighted Citation Impact
- 0.00