Decoding the peripheral transcriptomic and meta-genomic response to music in autism spectrum disorder via saliva-based RNA sequencing
Saliva-based RNA-seq can stably capture transcriptomic and microbial responses to behavioral stimuli. Music exposure modulates neuroimmune pathways relevant to autism, supporting the biological plausibility of music therapy and demonstrating saliva-based RNA-seq as a viable, non-invasive tool for monitoring intervention outcomes.
Authors
- Antonio Salas (ORCID: https://orcid.org/0000-0002-2336-702X)
- Alberto Gómez‐Carballa (ORCID: https://orcid.org/0000-0003-0927-1272)
- Federico Martinón‐Torres (ORCID: https://orcid.org/0000-0002-9023-581X)
- Laura Navarro (ORCID: https://orcid.org/0000-0002-2129-6010)
- Nour El Zahraa Mallah
- Andrea Cavenaghi
Institutions
- Complejo Hospitalario Universitario de Santiago (ES)
- Centro de Investigación Biomédica en Red de Enfermedades Respiratorias (ES)
- Instituto de Investigación Sanitaria de Santiago (ES)
Publication Details
- Journal
- Frontiers in Molecular Biosciences
- Published
- 2025-11-24
- DOI
- https://doi.org/10.3389/fmolb.2025.1696704
- Primary Topic
- Autism Spectrum Disorder Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- European Commission
- Ministerio de Ciencia e Innovación
- Instituto de Salud Carlos III
- European Regional Development Fund
- Interreg