Genenames.org: the HGNC and PGNC resources in 2026
The HUGO Gene Nomenclature Committee (HGNC), based at the University of Cambridge, approves unique symbols and descriptive names for human genes. The HGNC database currently contains over 44 400 approved gene symbols, over 19 250 of which represent protein-coding genes, ∼14 500 represent pseudogenes, and over 9500 represent non-coding RNA genes. The public website, www.genenames.org, displays all approved nomenclature within manually curated Symbol Reports and also displays related groups of genes in Gene Group Reports. In 2024, we formed the Plant Gene Nomenclature Committee (PGNC), which has been approving gene symbols and names for the tree species Populus trichocarpa. All approved plant gene nomenclature is displayed on the new website plant.genenames.org. Here, we review updates to the HGNC project and introduce the PGNC project.
Authors
- Kristian Gray (ORCID: https://orcid.org/0000-0002-7035-7107)
- Bryony Braschi (ORCID: https://orcid.org/0000-0002-5269-0985)
- Ruth L. Seal (ORCID: https://orcid.org/0000-0002-7545-6817)
- Elspeth A. Bruford (ORCID: https://orcid.org/0000-0002-8380-5247)
- Susan Tweedie (ORCID: https://orcid.org/0000-0003-1818-8243)
- James McClay
Institutions
- Cambridge School (PT)
Publication Details
- Journal
- Nucleic Acids Research
- Published
- 2025-11-25
- DOI
- https://doi.org/10.1093/nar/gkaf1229
- Citations
- 5
- Primary Topic
- Genomics and Phylogenetic Studies
- Type
- article
- Field-Weighted Citation Impact
- 4.03
Funders
- U.S. Department of Energy
- University of Cambridge
- University of Oxford
- National Institutes of Health