Glycemic Improvement with Low-Dose Dulaglutide Is Associated with Leptin and Obestatin Modulation in Type 2 Diabetes Mellitus
Dulaglutide improved glycemic control through mechanisms beyond weight reduction. Hormonal changes in leptin, adiponectin, and obestatin may help predict responses to GLP-1 RAs therapy.
Authors
- Ji Hee Yu (ORCID: https://orcid.org/0000-0003-1907-2859)
- Hyun Joo Cho
- Da Young Lee
- Ji A Seo (ORCID: https://orcid.org/0000-0002-1927-2618)
- Nan Hee Kim (ORCID: https://orcid.org/0000-0003-4378-520X)
- Inha Jung (ORCID: https://orcid.org/0000-0001-8561-8544)
- Hangseok Choi (ORCID: https://orcid.org/0000-0001-7412-8160)
- So Young Park (ORCID: https://orcid.org/0000-0002-8625-6968)
- In Young Choi (ORCID: https://orcid.org/0000-0001-8581-7471)
Institutions
- Korea University (KR)
- Korea University Medical Center (KR)
- Ansan University (KR)
Publication Details
- Journal
- Diabetes & Metabolism Journal
- Published
- 2025-11-24
- DOI
- https://doi.org/10.4093/dmj.2025.0681
- Primary Topic
- Diabetes Treatment and Management
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Korean Diabetes Association
- National Research Foundation
- Inha University
- Korea University
- National Research Foundation of Korea
- Ministry of Science and ICT, South Korea