Identification of multi-drug resistant Acinetobacter baumannii phage YZ2 and evaluation of its therapeutic efficacy in vivo and in vitro
Moreover, compared with the use of phage or polymyxin B alone, the combined use of phage YZ2 and polymyxin B can significantly increased the survival rate of <i>G. mellonella</i> larvae and had a synergistic effect. These results imply that phage YZ2 has the potential for development as an antimicrobial agent.
Authors
- Ann Cai
- Hongmei Chen (ORCID: https://orcid.org/0000-0002-8943-6139)
- Lihua Xiao (ORCID: https://orcid.org/0000-0001-8532-2727)
- Qingping Fu
- Yaru Zhi
- Yungang Wang (ORCID: https://orcid.org/0000-0002-8893-7636)
- Mingzhong Sun (ORCID: https://orcid.org/0000-0001-9001-4796)
- Dongmei Yan (ORCID: https://orcid.org/0000-0003-4863-2122)
- Qinfang Tang
Institutions
- Yancheng Third People's Hospital (CN)
Publication Details
- Journal
- Frontiers in Microbiology
- Published
- 2025-11-24
- DOI
- https://doi.org/10.3389/fmicb.2025.1657539
- Primary Topic
- Bacteriophages and microbial interactions
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Nantong University