A pharmacovigilance study of Bruton’s tyrosine kinase inhibitors: a multidimensional analysis based on FAERS and VigiBase
These results will provide new data to support the use of BTKis and further safety warnings. However, as a hypothesis-generating approach, it does not establish a definitive causal relationship, which will require further research and validation.
Authors
- Zhenhua Wu (ORCID: https://orcid.org/0000-0002-5527-0310)
- Han Qu (ORCID: https://orcid.org/0000-0001-9701-4748)
- Z. Li (ORCID: https://orcid.org/0009-0001-7015-8060)
- Yuqi Jia (ORCID: https://orcid.org/0000-0003-2869-975X)
- Zizhen Liu (ORCID: https://orcid.org/0009-0004-9966-7960)
- Xin Zhao (ORCID: https://orcid.org/0000-0001-8502-0139)
- Guorong Fan
- Yuefen Lou (ORCID: https://orcid.org/0009-0005-9622-6059)
Institutions
- Tongji University (CN)
- Shanghai Jiao Tong University (CN)
- Peking University (CN)
- Shanghai Tenth People's Hospital (CN)
- Peking University Third Hospital (CN)
Publication Details
- Journal
- Frontiers in Immunology
- Published
- 2025-11-25
- DOI
- https://doi.org/10.3389/fimmu.2025.1636657
- Primary Topic
- Pharmacovigilance and Adverse Drug Reactions
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Bethune Charitable Foundation
- Wu Jieping Medical Foundation