SLC11A1 protein as a key regulator of iron metabolism, ferroptosis mediator, and putative therapeutic target in nonalcoholic fatty liver disease: an integrated bioinformatics analysis

This study successfully identified specific proteins related to iron metabolism/ferroptosis pathways, such as ERN1 and SLC11A1, which demonstrate significant diagnostic potential for NAFLD, with SLC11A1 potentially possessing greater diagnostic value as a biomarker. The findings enhance the understanding of the genetically regulated pathogenesis of NAFLD and provide an important foundation for developing innovative diagnostic approaches and therapeutic interventions based on these targets.