Imaging-driven diagnosis of retroperitoneal psoas major alveolar soft part sarcoma: a case report

Alveolar soft part sarcoma (ASPS) is an infrequent and malignant soft tissue tumor with an elusive tissue origin. Its occurrence in the retroperitoneal psoas major muscle is extremely rare. The tumor's deep retroperitoneal location, complex anatomy, and hypervascularity pose challenges to preoperative diagnosis and surgical intervention. This case report presents a 21-year-old female diagnosed with left retroperitoneal psoas major ASPS. Advanced imaging modalities, such as computed tomography (CT) multidirectional reconstruction, magnetic resonance imaging (MRI), and three-dimensional (3D) rendering, were utilized. These imaging techniques not only clearly depicted the tumor's characteristics but also its spatial relationships with surrounding tissues and the vascular network. The detailed preoperative vascular assessment enabled the surgical team to comprehend the tumor anatomy and meticulously plan the approach, thus significantly reducing surgical risks and potential complications. The procedures and outcomes of this case offer valuable insights for clinical practice, highlighting the crucial role of imaging in the diagnosis and treatment of rare ASPS cases.

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Publication Details

Journal
Frontiers in Oncology
Published
2025-11-25
DOI
https://doi.org/10.3389/fonc.2025.1609432
Primary Topic
Sarcoma Diagnosis and Treatment
Type
article
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article

Imaging-driven diagnosis of retroperitoneal psoas major alveolar soft part sarcoma: a case report

Mingguang He, Wenfu Li, Lin Liu, Gaofeng Fan et al.
Frontiers in Oncology
Sarcoma Diagnosis and Treatment
article

Imaging-driven diagnosis of retroperitoneal psoas major alveolar soft part sarcoma: a case report

Mingguang He, Wenfu Li, Lin Liu, Gaofeng Fan, Shasha Wei
article en

Abstract

Alveolar soft part sarcoma (ASPS) is an infrequent and malignant soft tissue tumor with an elusive tissue origin. Its occurrence in the retroperitoneal psoas major muscle is extremely rare. The tumor's deep retroperitoneal location, complex anatomy, and hypervascularity pose challenges to preoperative diagnosis and surgical intervention. This case report presents a 21-year-old female diagnosed with left retroperitoneal psoas major ASPS. Advanced imaging modalities, such as computed tomography (CT) multidirectional reconstruction, magnetic resonance imaging (MRI), and three-dimensional (3D) rendering, were utilized. These imaging techniques not only clearly depicted the tumor's characteristics but also its spatial relationships with surrounding tissues and the vascular network. The detailed preoperative vascular assessment enabled the surgical team to comprehend the tumor anatomy and meticulously plan the approach, thus significantly reducing surgical risks and potential complications. The procedures and outcomes of this case offer valuable insights for clinical practice, highlighting the crucial role of imaging in the diagnosis and treatment of rare ASPS cases.

Frontiers in OncologyVol. 15
Zunyi Medical University (CN), Affiliated Hospital of Guizhou Medical University (CN), Huizhou Central People's Hospital (CN), Guangdong Academy of Medical Sciences (CN), Affiliated Hospital of Zunyi Medical College (CN)
Openalex Percentile: Top 48%
Sarcoma Diagnosis and Treatment
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