Structural and functional characterizations of infectivity and immune evasion of SARS-CoV-2 Omicron

In the originally published version of this paper, the authors noted errors in several parts of the manuscript.In Figure 5C, a typographical error appeared in the table: ''Omicron+R346R'' should read ''Omicron+R346K.''In the STAR Methods section, within the ''Recombinant DNA'' section of the key resources table (the third row, the first column), the mutation ''Q493K'' should be corrected to ''Q493R.''The same correction applies to the second line on page e3 of the PDF, where ''Q493K'' should also be ''Q493R.'' In Figure 3F, during image analysis, the same raw negative-stain EM image was accidentally reused in different panels due to a filesaving oversight.Because of the large size of the images, the authors zoomed in to highlight representative parts of the images for detailed observation.The image-saving software automatically stored new files in the last-used directory when they forgot to manually change the path of the folder, which led to duplicate files saved in two folders.This resulted in the raw images for ''Omicron-ACE2 & Trypsin'' and ''Delta-apo'' mistakenly being used for preparing the panels of ''WT-ACE2 & Trypsin'' and ''WT-apo,'' respectively, When zooming in on different regions, the raw image for ''Omicron-ACE2 & Trypsin'' was used both for the ''Omicron-ACE2 & Trypsin'' panel and mistakenly for the ''WT-ACE2 & Trypsin'' panel, causing partial overlap in the published figure.Similarly, the raw image for ''Delta-apo'' was used both for the ''Delta-apo'' panel and mistakenly for the ''WT-apo'' panel, leading to partial overlap.The authors apologize for any confusion these errors may have caused.

Authors

Publication Details

Journal
Cell
Published
2025-11-25
DOI
https://doi.org/10.1016/j.cell.2025.11.025
Primary Topic
SARS-CoV-2 and COVID-19 Research
Type
article
Field-Weighted Citation Impact
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article

Structural and functional characterizations of infectivity and immune evasion of SARS-CoV-2 Omicron

Yunlong Cao, Ge Xu, Xiangxi Wang, Qianhui Zhu et al.
Cell
SARS-CoV-2 and COVID-19 Research
article

Structural and functional characterizations of infectivity and immune evasion of SARS-CoV-2 Omicron

Yunlong Cao, Ge Xu, Xiangxi Wang, Qianhui Zhu, Zijing Jia, Kaiyue Fan, Tianming Chu, Ruihong Chen, Pan Liu, Peng Yang, Xinran Pei, Leilei Feng, Yide Wang, Boling Zhu, Rui Feng, Lei Wang, Kang Wang, Nan Wang, Wangjun Fu, X. Sunney Xie, Minnan Yang, Zhen Cui
article en

Abstract

In the originally published version of this paper, the authors noted errors in several parts of the manuscript.In Figure 5C, a typographical error appeared in the table: ''Omicron+R346R'' should read ''Omicron+R346K.''In the STAR Methods section, within the ''Recombinant DNA'' section of the key resources table (the third row, the first column), the mutation ''Q493K'' should be corrected to ''Q493R.''The same correction applies to the second line on page e3 of the PDF, where ''Q493K'' should also be ''Q493R.'' In Figure 3F, during image analysis, the same raw negative-stain EM image was accidentally reused in different panels due to a filesaving oversight.Because of the large size of the images, the authors zoomed in to highlight representative parts of the images for detailed observation.The image-saving software automatically stored new files in the last-used directory when they forgot to manually change the path of the folder, which led to duplicate files saved in two folders.This resulted in the raw images for ''Omicron-ACE2 & Trypsin'' and ''Delta-apo'' mistakenly being used for preparing the panels of ''WT-ACE2 & Trypsin'' and ''WT-apo,'' respectively, When zooming in on different regions, the raw image for ''Omicron-ACE2 & Trypsin'' was used both for the ''Omicron-ACE2 & Trypsin'' panel and mistakenly for the ''WT-ACE2 & Trypsin'' panel, causing partial overlap in the published figure.Similarly, the raw image for ''Delta-apo'' was used both for the ''Delta-apo'' panel and mistakenly for the ''WT-apo'' panel, leading to partial overlap.The authors apologize for any confusion these errors may have caused.

CellVol. 188(25)
Openalex Percentile: Top 58%
SARS-CoV-2 and COVID-19 Research
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