Pediatric dentinogenic ghost cell tumor: a case report and review of the literature
Dentinogenic ghost cell tumor (DGCT) is a rare odontogenic neoplasm that presents with nonspecific clinical manifestations and imaging features. It is more prevalent in elderly patients, with cases in children being extremely rare. This article presents a case study of a 10-year-old male patient who exhibited symptoms of swelling and pain in the left cheek for a duration of two weeks. Cone beam computed tomography (CBCT) demonstrated a hypodense lesion involving the left maxilla, with extension into the maxillary sinus and buccal cortical expansion. The patient underwent decompression, and histopathological examination of the intraoperative specimen suggested a diagnosis of calcifying odontogenic cyst (COC). One year after decompression, the patient underwent a tumor resection and the diagnosis of DGCT was confirmed by the post-operative pathology. Six months after tumor resection, CBCT showed complete bone remodeling in the lesion area. The patient is currently undergoing regular follow-up. This case provides an important reference for the diagnosis and treatment of pediatric DGCT, helping clinicians to develop individualised treatment plans.
Authors
- Hongsheng Tian (ORCID: https://orcid.org/0000-0002-9003-0371)
- Jingchao Han (ORCID: https://orcid.org/0000-0002-8037-7056)
- Linlin Wang (ORCID: https://orcid.org/0000-0003-4950-8748)
- Jianli Xie (ORCID: https://orcid.org/0009-0004-1174-2664)
Institutions
- Shandong University of Traditional Chinese Medicine (CN)
- Jinan Stomatological Hospital (CN)
- Affiliated Hospital of Shandong University of Traditional Chinese Medicine (CN)
Publication Details
- Journal
- Frontiers in Oncology
- Published
- 2025-11-25
- DOI
- https://doi.org/10.3389/fonc.2025.1665311
- Primary Topic
- Oral and Maxillofacial Pathology
- Type
- article
- Field-Weighted Citation Impact
- 0.00