APOL1 is a novel prognostic biomarker in thyroid cancer and correlates with immune infiltration
In this study, we innovatively explored the potential association between APOL1 and the immune microenvironment, and demonstrated that APOL1 expression is upregulated in THCA tissues. Knockdown of APOL1 in THCA cells results in promoted proliferation and migration. Additionally, APOL1 may regulate ICI in the THCA microenvironment.
Authors
- Tiefeng Shi (ORCID: https://orcid.org/0000-0001-9443-0711)
- Xiang Tao (ORCID: https://orcid.org/0000-0002-1052-118X)
- Zongyuan Zhang
- Jianting Man
Institutions
- Harbin Medical University (CN)
- Southwest Medical University (CN)
- Second Affiliated Hospital of Harbin Medical University (CN)
Publication Details
- Journal
- Frontiers in Oncology
- Published
- 2025-11-25
- DOI
- https://doi.org/10.3389/fonc.2025.1707078
- Citations
- 1
- Primary Topic
- Renal Diseases and Glomerulopathies
- Type
- article
- Field-Weighted Citation Impact
- 1.43
Funders
- Harbin Medical University