The role of TMEM59L in colorectal cancer progression and its interaction with the TGF-β/Smad pathway
TMEM59L may promote CRC metastasis by enhancing cell migration and invasion, with minimal impact on cell proliferation, potentially through the TGF-β/Smad signaling pathway.
Authors
- Lingyi Chen (ORCID: https://orcid.org/0000-0002-3695-3407)
- Jiafei Liu (ORCID: https://orcid.org/0000-0001-9744-2232)
- Peishi Jiang (ORCID: https://orcid.org/0000-0001-7334-7660)
- Siwei Zhu (ORCID: https://orcid.org/0009-0002-5951-6784)
- Yi Sun (ORCID: https://orcid.org/0000-0001-8169-0530)
- Hongjie Yang
Institutions
- Nankai University (CN)
- Tianjin First Center Hospital (CN)
- Tianjin Municipal Engineering Design and Research Institute (CN)
- Tianjin Medical University (CN)
Publication Details
- Journal
- Frontiers in Oncology
- Published
- 2025-11-25
- DOI
- https://doi.org/10.3389/fonc.2025.1674849
- Primary Topic
- TGF-β signaling in diseases
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Science Foundation
- National Natural Science Foundation of China
- Nankai University