Identifying serum microRNAs as biomarkers for endometriosis in adolescents and young adults

This is the first study to reveal the differential abundance of microRNAs specifically in adolescent patients with endometriosis. There are distinct differences from those identified in adult women with endometriosis. Our findings present a unique signature of microRNA found in the serum of adolescents with endometriosis. This finding may be useful as a noninvasive biomarker to diagnose early disease in adolescents. Non-invasive diagnosis may allow for early diagnosis and prevention of disease progression.

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Publication Details

Journal
Reproductive Biology and Endocrinology
Published
2025-11-24
DOI
https://doi.org/10.1186/s12958-025-01502-z
Primary Topic
Endometriosis Research and Treatment
Type
article
Field-Weighted Citation Impact
0.00
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article

Identifying serum microRNAs as biomarkers for endometriosis in adolescents and young adults

Alla Vash‐Margita, Daniel A. Morgenstern, Ramanaiah Mamillapalli, Hugh S. Taylor et al.
Reproductive Biology and Endocrinology
Endometriosis Research and Treatment
article

Identifying serum microRNAs as biomarkers for endometriosis in adolescents and young adults

Alla Vash‐Margita, Daniel A. Morgenstern, Ramanaiah Mamillapalli, Hugh S. Taylor, Karthik Pyneni
article en

Abstract

This is the first study to reveal the differential abundance of microRNAs specifically in adolescent patients with endometriosis. There are distinct differences from those identified in adult women with endometriosis. Our findings present a unique signature of microRNA found in the serum of adolescents with endometriosis. This finding may be useful as a noninvasive biomarker to diagnose early disease in adolescents. Non-invasive diagnosis may allow for early diagnosis and prevention of disease progression.

Reproductive Biology and EndocrinologyVol. 23(1)
Yale University (US)
Openalex Percentile: Top 54%
Endometriosis Research and Treatment
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