Identifying serum microRNAs as biomarkers for endometriosis in adolescents and young adults
This is the first study to reveal the differential abundance of microRNAs specifically in adolescent patients with endometriosis. There are distinct differences from those identified in adult women with endometriosis. Our findings present a unique signature of microRNA found in the serum of adolescents with endometriosis. This finding may be useful as a noninvasive biomarker to diagnose early disease in adolescents. Non-invasive diagnosis may allow for early diagnosis and prevention of disease progression.
Authors
- Alla Vash‐Margita (ORCID: https://orcid.org/0000-0002-3510-3945)
- Daniel A. Morgenstern (ORCID: https://orcid.org/0000-0002-4859-1108)
- Ramanaiah Mamillapalli (ORCID: https://orcid.org/0000-0002-4022-8910)
- Hugh S. Taylor (ORCID: https://orcid.org/0000-0003-1720-8310)
- Karthik Pyneni
Institutions
- Yale University (US)
Publication Details
- Journal
- Reproductive Biology and Endocrinology
- Published
- 2025-11-24
- DOI
- https://doi.org/10.1186/s12958-025-01502-z
- Primary Topic
- Endometriosis Research and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 0.00