Severe hypotensive transfusion reaction in a patient with liver dysfunction: A case report
This case highlights the importance of recognising bradykinin-mediated HyTRs during FFP transfusion, especially in patients with liver dysfunction where impaired bradykinin degradation may contribute to accumulation. Prompt recognition, exclusion of alternative causes, and supportive management are crucial for favourable outcomes.
Authors
- Jubin Joseph (ORCID: https://orcid.org/0000-0003-3674-6974)
- Jeeva George (ORCID: https://orcid.org/0000-0002-0653-0366)
- Priya Prasad (ORCID: https://orcid.org/0009-0000-2164-0080)
- Vandana G. Hari
- A. H. Francis
Institutions
- Caritas Hospital (IN)
Publication Details
- Journal
- Transfusion Medicine
- Published
- 2025-11-24
- DOI
- https://doi.org/10.1111/tme.70048
- Primary Topic
- Trauma, Hemostasis, Coagulopathy, Resuscitation
- Type
- article
- Field-Weighted Citation Impact
- 0.00