Protective effects of treprostinil and ischemic preconditioning on hepatic ischemia-reperfusion injury and biomarkers in experimental studies in rats
HIRI results in oxidative stress and cytokine overexpression, which deteriorate hepatic function and accelerates myocardial damage. Treprostinil and IP are promising strategies for preventing reperfusion-induced cellular and systemic damage.
Authors
- Serafeim‐Chrysovalantis Kotoulas (ORCID: https://orcid.org/0000-0002-6092-1341)
- Emmanouela P. Apostolopoulou (ORCID: https://orcid.org/0000-0002-7642-7946)
- Christina Mouratidou (ORCID: https://orcid.org/0009-0007-8657-2032)
- I. Galanis (ORCID: https://orcid.org/0000-0002-5844-0477)
- Georgios Katsanos (ORCID: https://orcid.org/0000-0002-5845-8175)
- Maria Papaioannou (ORCID: https://orcid.org/0000-0003-3149-6523)
- T. Pavlidis (ORCID: https://orcid.org/0000-0002-8141-1412)
- Georgia D. Brellou (ORCID: https://orcid.org/0000-0003-0588-7256)
- Georgios Tsoulfas (ORCID: https://orcid.org/0000-0001-5043-7962)
Institutions
- Aristotle University of Thessaloniki (GR)
Publication Details
- Journal
- World Journal of Gastrointestinal Surgery
- Published
- 2025-11-25
- DOI
- https://doi.org/10.4240/wjgs.v17.i11.110864
- Primary Topic
- Organ Transplantation Techniques and Outcomes
- Type
- article
- Field-Weighted Citation Impact
- 0.00