The Possible Role of Neurofilament Light Chain as a Serum Biomarker in Anorexia Nervosa: Clinical Implications
Clinical remission in AN appears to be linked to a decrease in both markers neuronal damage and hypothalamic autoimmunity. However, as elevated serum NfL is observed across a spectrum of neurological and psychiatric disorders, its specificity as a biomarker for AN should be further investigated. While NfL may reflect neuroaxonal injury in AN, its interpretation should be contextualized within a broader clinical and immunological framework.
Authors
- Benedetta Conio (ORCID: https://orcid.org/0000-0002-8201-7193)
- Samir Giuseppe Sukkar (ORCID: https://orcid.org/0000-0003-4194-1547)
- Danièle Saverino (ORCID: https://orcid.org/0000-0002-1623-1116)
- Antonella Strangio
- Andrea Amerio (ORCID: https://orcid.org/0000-0002-3439-340X)
- Eleonora Martino
- Andrea Aguglia (ORCID: https://orcid.org/0000-0002-2003-2101)
Institutions
- Ospedale Policlinico San Martino (IT)
- University of Genoa (IT)
Publication Details
- Journal
- Biomolecules
- Published
- 2025-11-22
- DOI
- https://doi.org/10.3390/biom15121644
- Primary Topic
- Eating Disorders and Behaviors
- Type
- article
- Field-Weighted Citation Impact
- 0.00