Interactive effects of high-density lipoprotein cholesterol and insulin resistance on depression: results from the NHANES (2005–2018)

Elevated HDL-C in the context of IR were associated with increased depression odds. These findings underscore the importance of considering IR when examining the relationship between HDL-C and neuropsychiatric disorders.

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Publication Details

Journal
Lipids in Health and Disease
Published
2025-11-24
DOI
https://doi.org/10.1186/s12944-025-02795-0
Primary Topic
Cardiac Health and Mental Health
Type
article
Field-Weighted Citation Impact
0.00

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article

Interactive effects of high-density lipoprotein cholesterol and insulin resistance on depression: results from the NHANES (2005–2018)

Liang Rao, Jie Li, Yuxin Hu, Xiaohua Xian et al.
Lipids in Health and Disease
Cardiac Health and Mental Health
article

Interactive effects of high-density lipoprotein cholesterol and insulin resistance on depression: results from the NHANES (2005–2018)

Liang Rao, Jie Li, Yuxin Hu, Xiaohua Xian, Yin Xian
article en

Abstract

Elevated HDL-C in the context of IR were associated with increased depression odds. These findings underscore the importance of considering IR when examining the relationship between HDL-C and neuropsychiatric disorders.

Lipids in Health and DiseaseVol. 24(1)
Nanchong Central Hospital (CN)
Jiangsu Development and Reform Commission, Natural Science Foundation of Sichuan Province
Openalex Percentile: Top 47%
Cardiac Health and Mental Health
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