Hippocampal-Avoidance Whole-Brain Radiotherapy: Dosimetric Comparison of 3D-CRT, IMRT, and VMAT for Brain Metastases from Lung Cancer
HA-WBRT with IMRT and VMAT significantly reduced the hippocampal dose while maintaining optimal PTV coverage. VMAT is preferred for its balance of efficacy, protection, and treatment time, while IMRT represents a feasible approach for facilities without VMAT, though it requires stricter dose control and longer treatment times.
Authors
- Hiba Omer (ORCID: https://orcid.org/0000-0002-1501-1760)
- Abdelmoneim Sulieman (ORCID: https://orcid.org/0000-0003-0830-4706)
- Dương Thanh Tài (ORCID: https://orcid.org/0000-0001-7276-8105)
- Nissren Tamam (ORCID: https://orcid.org/0000-0001-9709-2754)
- Hind Toufig
- Thi Thao (ORCID: https://orcid.org/0000-0003-3776-500X)
- D.A. Bradley (ORCID: https://orcid.org/0000-0001-9485-5242)
- Nguyen Thuong Nghia
- Le Ba Thach
- Tran Nhat My
Institutions
- Princess Nourah bint Abdulrahman University (SA)
- King Saud bin Abdulaziz University for Health Sciences (SA)
- King Faisal Specialist Hospital & Research Centre (SA)
- University of Surrey (GB)
- Trường ĐH Nguyễn Tất Thành (VN)
- Khanh Hoa General Hospital (VN)
- Pham Ngoc Thach Hospital (VN)
- King Faisal University (SA)
- Imam Abdulrahman Bin Faisal University (SA)
- Sunway University (MY)
Publication Details
- Journal
- Cancers
- Published
- 2025-11-24
- DOI
- https://doi.org/10.3390/cancers17233744
- Primary Topic
- Brain Metastases and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 0.00