Abnormal cholesterol–cholesteryl ester metabolism impairs mouse oocyte quality during ovarian aging
This study reveals the mechanism by which cholesterol-cholesteryl ester metabolism regulates oocyte quality and thus participates in the process of oocyte aging by influencing mitophagy and mitochondrial function.
Authors
- Lijun Ding (ORCID: https://orcid.org/0000-0002-6330-7945)
- Xin Zhen
- Guijun Yan (ORCID: https://orcid.org/0000-0003-3009-7547)
- Nannan Kang (ORCID: https://orcid.org/0000-0001-5746-5691)
- Sainan Zhang (ORCID: https://orcid.org/0000-0001-7258-4592)
- Yang Zhang (ORCID: https://orcid.org/0000-0001-8474-5947)
- Shanshan Wang (ORCID: https://orcid.org/0000-0002-9416-0050)
- Haixiang Sun (ORCID: https://orcid.org/0000-0002-1215-1792)
- Chuanming Liu (ORCID: https://orcid.org/0000-0003-0678-9092)
- Die Wu
- Junshun Fang
- Yicen Liu
- Bichun Guo
Institutions
- Nanjing Normal University (CN)
- Nanjing Drum Tower Hospital (CN)
- Nanjing Medical University (CN)
- Nanjing University (CN)
Publication Details
- Journal
- Cellular & Molecular Biology Letters
- Published
- 2025-11-24
- DOI
- https://doi.org/10.1186/s11658-025-00811-w
- Citations
- 1
- Primary Topic
- Reproductive Biology and Fertility
- Type
- article
- Field-Weighted Citation Impact
- 1.88
Funders
- National Natural Science Foundation of China
- China Postdoctoral Science Foundation
- Nanjing University
- Nanjing Drum Tower Hospital