WA-NET: enhanced boundary-aware segmentation of skin lesions via frequency-spatial feature fusion and attention-guided edge refinement

Skin cancer remains a major public health concern due to its high morbidity and mortality rates. While automatic segmentation techniques have improved diagnostic accuracy, they continue to face challenges such as artefacts, small lesion detection, and poor contrast between lesions and surrounding tissue. To overcome these limitations, we propose WA-NET, a novel skin lesion segmentation network that integrates a Boundary Refinement module (BRM) and an Enhanced Wavelet Transform (EWT) module. The BRM employs independent edge detection branches to enhance boundary representation, particularly in low-contrast regions. The EWT module adaptively fuses multi-scale, multi-directional sub-band features in the frequency domain to better capture texture and structural details. Furthermore, a composite loss function combining binary cross-entropy, Dice loss, and edge-supervised loss is introduced to improve both global segmentation accuracy and local boundary precision. WA-NET achieves state-of-the-art performance on three benchmark datasets-ISIC2017 (DSC: 0.9395, SE: 0.9357, ACC: 0.9573), ISIC2018 (DSC: 0.9458, SE: 0.9460, ACC: 0.9610), and PH2 (DSC: 0.9517, SE: 0.9593, ACC: 0.9638)-demonstrating strong robustness and superior boundary segmentation under challenging imaging conditions.

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Publication Details

Journal
Scientific Reports
Published
2025-11-24
DOI
https://doi.org/10.1038/s41598-025-25583-3
Primary Topic
Cutaneous Melanoma Detection and Management
Type
article
Field-Weighted Citation Impact
0.00

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article

WA-NET: enhanced boundary-aware segmentation of skin lesions via frequency-spatial feature fusion and attention-guided edge refinement

Wen Zhu, Qingbo Li, Gary G. Hu, Xinyi Liao
Scientific Reports
Cutaneous Melanoma Detection and Management
article

WA-NET: enhanced boundary-aware segmentation of skin lesions via frequency-spatial feature fusion and attention-guided edge refinement

Wen Zhu, Qingbo Li, Gary G. Hu, Xinyi Liao
article en

Abstract

Skin cancer remains a major public health concern due to its high morbidity and mortality rates. While automatic segmentation techniques have improved diagnostic accuracy, they continue to face challenges such as artefacts, small lesion detection, and poor contrast between lesions and surrounding tissue. To overcome these limitations, we propose WA-NET, a novel skin lesion segmentation network that integrates a Boundary Refinement module (BRM) and an Enhanced Wavelet Transform (EWT) module. The BRM employs independent edge detection branches to enhance boundary representation, particularly in low-contrast regions. The EWT module adaptively fuses multi-scale, multi-directional sub-band features in the frequency domain to better capture texture and structural details. Furthermore, a composite loss function combining binary cross-entropy, Dice loss, and edge-supervised loss is introduced to improve both global segmentation accuracy and local boundary precision. WA-NET achieves state-of-the-art performance on three benchmark datasets-ISIC2017 (DSC: 0.9395, SE: 0.9357, ACC: 0.9573), ISIC2018 (DSC: 0.9458, SE: 0.9460, ACC: 0.9610), and PH2 (DSC: 0.9517, SE: 0.9593, ACC: 0.9638)-demonstrating strong robustness and superior boundary segmentation under challenging imaging conditions.

Scientific ReportsVol. 15(1)
Hainan Normal University (CN), China United Network Communications Group (China) (CN)
National Natural Science Foundation of China, Natural Science Foundation of Hainan Province, National Key Research and Development Program of China, Division of Graduate Education
Openalex Percentile: Top 51%
Cutaneous Melanoma Detection and Management
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WA-NET: enhanced boundary-aware segmentation of skin lesions via frequency-spatial feature fusion and attention-guided edge refinement — Wen Zhu, Qingbo Li, et al. · Scientific Reports (2025) | TGRS Research Map | TGRS