Phillyrin improves pulmonary epithelial barrier dysfunction in LPS-induced acute lung injury through the RhoA/ROCK signaling pathway
Phillyrin inhibits pulmonary edema, suppresses inflammation and oxidative stress in ALI rats, and improves LPS-induced alveolar epithelial barrier dysfunction by inhibiting RhoA/ROCK pathways.
Authors
- Bingbing Cheng (ORCID: https://orcid.org/0000-0002-1336-4781)
- Yiming Zhuang (ORCID: https://orcid.org/0000-0001-9482-5289)
- Yubin Ke (ORCID: https://orcid.org/0000-0002-4983-7755)
- Li‐Mei Li
- Qianyuan Wu
- Yinghao Wang (ORCID: https://orcid.org/0000-0002-1928-0538)
- Meixia Huang
- Yingzheng Wang (ORCID: https://orcid.org/0009-0006-1570-3624)
Institutions
- Fujian University of Traditional Chinese Medicine (CN)
Publication Details
- Journal
- Journal of Pharmacy and Pharmacology
- Published
- 2025-11-24
- DOI
- https://doi.org/10.1093/jpp/rgaf115
- Primary Topic
- Neonatal Respiratory Health Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00