Comparative efficacy of multiple drugs for non-alcoholic fatty liver disease: a Bayesian network meta-analysis

The present study suggests that GLP-1RA may be the optimal treatment for NAFLD patients. In addition, current evidence does not sufficiently evaluate the impact of SGLT-2I on reducing liver fat content or histological outcomes. The potential risk of weight gain associated with TZD appears to be a limitation to their use. Vitamin E may be a suitable option for nondiabetic patients with NAFLD.

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Publication Details

Journal
European journal of medical research
Published
2025-11-24
DOI
https://doi.org/10.1186/s40001-025-03445-y
Citations
1
Primary Topic
Liver Disease Diagnosis and Treatment
Type
article
Field-Weighted Citation Impact
1.35

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article

Comparative efficacy of multiple drugs for non-alcoholic fatty liver disease: a Bayesian network meta-analysis

ZhiMin Xiao, Jiahong Gong, Xiao‐Nan Li, Feng Zhou
1 citations
European journal of medical research
Liver Disease Diagnosis and Treatment
1.35
article

Comparative efficacy of multiple drugs for non-alcoholic fatty liver disease: a Bayesian network meta-analysis

ZhiMin Xiao, Jiahong Gong, Xiao‐Nan Li, Feng Zhou
article en
1 citations

Abstract

The present study suggests that GLP-1RA may be the optimal treatment for NAFLD patients. In addition, current evidence does not sufficiently evaluate the impact of SGLT-2I on reducing liver fat content or histological outcomes. The potential risk of weight gain associated with TZD appears to be a limitation to their use. Vitamin E may be a suitable option for nondiabetic patients with NAFLD.

European journal of medical researchVol. 30(1)
Wuhan University (CN), Zhongnan Hospital of Wuhan University (CN)
National Natural Science Foundation of China
Openalex Percentile: Top 14%
Liver Disease Diagnosis and Treatment
1.35
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