Neutrophil-to-lymphocyte ratio predicts mortality for sepsis-induced coagulopathy: a retrospective study
NLR is significantly associated with mortality in SIC patients and can predict short-and long-term mortality. This finding suggests that the NLR may be useful in identifying patients with SIC at high risk of mortality. Elevated NLR is significantly associated with increased mortality in SIC patients and can predict short-and long-term mortality. The relationship between NLR and mortality risk is J-shaped, with the lowest risk observed in the second quartile. While NLR demonstrates modest predictive value, its accessibility and ease of use make it a potentially valuable tool for early risk stratification and informing clinical decision-making in SIC patients, especially in emergencies or resource-limited settings.
Authors
- Shangwen Pan (ORCID: https://orcid.org/0000-0003-4149-2235)
- Guangyan Yan (ORCID: https://orcid.org/0000-0003-1531-5446)
- Huaqing Shu
- Hui Zhong (ORCID: https://orcid.org/0000-0002-6909-6456)
- Chaolin Huang (ORCID: https://orcid.org/0000-0001-6240-7963)
Institutions
- Jinyintan Hospital (CN)
- Jiangxi Provincial People's Hospital (CN)
- Union Hospital (CN)
- Huazhong University of Science and Technology (CN)
Publication Details
- Journal
- European journal of medical research
- Published
- 2025-11-24
- DOI
- https://doi.org/10.1186/s40001-025-03428-z
- Citations
- 1
- Primary Topic
- Sepsis Diagnosis and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 1.35