Expression and Roles of Free Radicals and Reactive Oxygen Species in Hearing Loss

Elevated ROS and free radicals appear to contribute to the pathogenesis of hearing loss. Although definitive conclusions cannot yet be drawn, current evidence suggests that antioxidant approaches may aid in prevention and treatment. Further studies are needed to elucidate underlying mechanisms, refine therapeutic targets and dosing, and validate efficacy in rigorously designed clinical trials.

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Publication Details

Journal
Antioxidants
Published
2025-11-24
DOI
https://doi.org/10.3390/antiox14121397
Citations
1
Primary Topic
Hearing, Cochlea, Tinnitus, Genetics
Type
article
Field-Weighted Citation Impact
1.46

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article

Expression and Roles of Free Radicals and Reactive Oxygen Species in Hearing Loss

Dong Keon Yon, H. Kim, Youn‐Jung Kim, Yeon Ju Oh et al.
1 citations
Antioxidants
Hearing, Cochlea, Tinnitus, Genetics
1.46
article

Expression and Roles of Free Radicals and Reactive Oxygen Species in Hearing Loss

Dong Keon Yon, H. Kim, Youn‐Jung Kim, Yeon Ju Oh, Sung Soo Kim, Jae Min Lee, Seung Geun Yeo, Yuelei Jin
article en
1 citations

Abstract

Elevated ROS and free radicals appear to contribute to the pathogenesis of hearing loss. Although definitive conclusions cannot yet be drawn, current evidence suggests that antioxidant approaches may aid in prevention and treatment. Further studies are needed to elucidate underlying mechanisms, refine therapeutic targets and dosing, and validate efficacy in rigorously designed clinical trials.

AntioxidantsVol. 14(12)
Kyung Hee University (KR), Kyung Hee University Medical Center (KR)
National Research Foundation, Korea Health Industry Development Institute, National Research Foundation of Korea
Openalex Percentile: Top 15%
Hearing, Cochlea, Tinnitus, Genetics
1.46
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