Kinetic modeling of multi-step transformations using sequential dynamic flow experiments
Dynamic experimentation was applied for a two-step continuous flow reaction. First a Paal–Knorr reaction was performed, followed by an S N Ar reaction. Implementation of multiple PAT enables kinetic modeling using Dynochem.
Authors
- Christopher A. Hone (ORCID: https://orcid.org/0000-0002-5939-920X)
- C. Oliver Kappe (ORCID: https://orcid.org/0000-0003-2983-6007)
- Florian Wagner (ORCID: https://orcid.org/0000-0003-4085-9496)
- Klara Silber (ORCID: https://orcid.org/0009-0005-4501-8233)
Institutions
- University of Graz (AT)
- Research Center Pharmaceutical Engineering (Austria) (AT)
Publication Details
- Journal
- Reaction Chemistry & Engineering
- Published
- 2025-11-12
- DOI
- https://doi.org/10.1039/d5re00306g
- Primary Topic
- Innovative Microfluidic and Catalytic Techniques Innovation
- Type
- article
- Field-Weighted Citation Impact
- 0.00