Artificial intelligence and radiological imaging in oncology: state of the art and future perspectives

Abstract Artificial intelligence (AI), in integration with the domain of radiogenomics, is transforming the perspective of oncology by bringing in imaging data with genomic profiles, to improve cancer diagnosis and treatment planning, and personalized therapies. AI-based models are more efficient for early detection of cancer, tumor-segmentation, and prediction of treatment responses, as seen in breast cancer radiomics applications. The developments have transformed the space for accuracy, workflow production, and reduced variability in image interpretation. It’s a long journey, as there are still many challenges such as data quality, data diversity, as well as ethical issues regarding privacy and trust. Regulation barriers also push waiting time for clinical adoption as these limitations must be overcome through interdisciplinary cooperation on a very strong data governance model to maximize the integration of AI in oncology. All of the conventional imaging techniques such as X-ray, CT, MRI, and PET scan are integral for staging, detecting metastasis, and evaluating treatment response. This review highlights the transformative role of artificial intelligence (AI) in oncology, focusing on its applications in radiological imaging and radiogenomics. It demonstrates how AI integrates imaging and genomic data to enhance cancer diagnosis, treatment planning, and personalized medicine. The review also examines the benefits of AI, such as improved diagnostic accuracy, workflow efficiency, and predictive capabilities for treatment responses. Additionally, it identifies goals like data quality, interpretability, ethical concerns, and regulatory hurdles, emphasizing the need for collaborative efforts to address these issues. The review provides a comprehensive overview of AI’s potential and limitations, paving the way for future advancements in oncology.

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Publication Details

Journal
Journal of Medical Imaging and Interventional Radiology
Published
2025-11-24
DOI
https://doi.org/10.1007/s44326-025-00085-8
Primary Topic
Radiomics and Machine Learning in Medical Imaging
Type
article
Field-Weighted Citation Impact
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article

Artificial intelligence and radiological imaging in oncology: state of the art and future perspectives

Carmine Picone, Vincenza Granata, Antonella Petrillo, Raffaella Mormile et al.
Journal of Medical Imaging and Interventional Radiology
Radiomics and Machine Learning in Medical Imaging
article

Artificial intelligence and radiological imaging in oncology: state of the art and future perspectives

Carmine Picone, Vincenza Granata, Antonella Petrillo, Raffaella Mormile, Maria Chiara Brunese, Roberta Fusco, Alessandro Ottaiano
article en

Abstract

Abstract Artificial intelligence (AI), in integration with the domain of radiogenomics, is transforming the perspective of oncology by bringing in imaging data with genomic profiles, to improve cancer diagnosis and treatment planning, and personalized therapies. AI-based models are more efficient for early detection of cancer, tumor-segmentation, and prediction of treatment responses, as seen in breast cancer radiomics applications. The developments have transformed the space for accuracy, workflow production, and reduced variability in image interpretation. It’s a long journey, as there are still many challenges such as data quality, data diversity, as well as ethical issues regarding privacy and trust. Regulation barriers also push waiting time for clinical adoption as these limitations must be overcome through interdisciplinary cooperation on a very strong data governance model to maximize the integration of AI in oncology. All of the conventional imaging techniques such as X-ray, CT, MRI, and PET scan are integral for staging, detecting metastasis, and evaluating treatment response. This review highlights the transformative role of artificial intelligence (AI) in oncology, focusing on its applications in radiological imaging and radiogenomics. It demonstrates how AI integrates imaging and genomic data to enhance cancer diagnosis, treatment planning, and personalized medicine. The review also examines the benefits of AI, such as improved diagnostic accuracy, workflow efficiency, and predictive capabilities for treatment responses. Additionally, it identifies goals like data quality, interpretability, ethical concerns, and regulatory hurdles, emphasizing the need for collaborative efforts to address these issues. The review provides a comprehensive overview of AI’s potential and limitations, paving the way for future advancements in oncology.

Journal of Medical Imaging and Interventional RadiologyVol. 12(1)
University of Molise (IT), Azienda Ospedaliera S.Giuseppe Moscati (IT), Istituto Nazionale Tumori IRCCS "Fondazione G. Pascale" (IT)
Openalex Percentile: Top 49%
Radiomics and Machine Learning in Medical Imaging
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