Endobronchial Recurrence of Renal Cell Carcinoma 12 Years After Nephrectomy: A Rare Case Treated With Microwave Coagulation Therapy

Endobronchial metastasis (EM) from renal cell carcinoma (RCC) is a rare manifestation of intrathoracic spread. RCC is known for its potential to recur long after nephrectomy, and EM may mimic primary lung cancer, complicating diagnosis and management. A 69-year-old male patient with a history of nephrectomy for RCC presented with progressive dyspnea. Imaging revealed a right hilar mass, and bronchoscopy identified a pedunculated polypoid lesion in the right main bronchus. Microwave coagulation therapy was performed to excise the lesion and achieve hemostasis. Histopathological analysis confirmed metastatic RCC. The patient was referred for systemic therapy following bronchoscopic intervention. This case highlights the diagnostic challenge of differentiating EM from primary lung cancer, especially in patients with a smoking history and elevated tumor markers. Bronchoscopic microwave coagulation therapy provided a safe and effective method for both diagnosis and airway management. Clinicians should remain vigilant for late recurrence of RCC, even more than a decade after nephrectomy. Bronchoscopic microwave coagulation therapy may serve as a minimally invasive option for the diagnosis and treatment of endobronchial lesions.

Authors

Institutions

Publication Details

Journal
Cureus
Published
2025-11-24
DOI
https://doi.org/10.7759/cureus.97695
Primary Topic
Tracheal and airway disorders
Type
article
Field-Weighted Citation Impact
0.00
Controls
|||
ALL TIME
JAN
FEB
MAR
APR
MAY
JUN
JUL
AUG
SEP
OCT
article

Endobronchial Recurrence of Renal Cell Carcinoma 12 Years After Nephrectomy: A Rare Case Treated With Microwave Coagulation Therapy

Takayuki Yamamoto, Hirofumi Nakano, Yuki Tsukasa, Yukihiro Sugimoto et al.
Cureus
Tracheal and airway disorders
article

Endobronchial Recurrence of Renal Cell Carcinoma 12 Years After Nephrectomy: A Rare Case Treated With Microwave Coagulation Therapy

Takayuki Yamamoto, Hirofumi Nakano, Yuki Tsukasa, Yukihiro Sugimoto, Ryota Aoki, Masanori Takayama, Shinya Abe, Tetsurou Takeuti
article en

Abstract

Endobronchial metastasis (EM) from renal cell carcinoma (RCC) is a rare manifestation of intrathoracic spread. RCC is known for its potential to recur long after nephrectomy, and EM may mimic primary lung cancer, complicating diagnosis and management. A 69-year-old male patient with a history of nephrectomy for RCC presented with progressive dyspnea. Imaging revealed a right hilar mass, and bronchoscopy identified a pedunculated polypoid lesion in the right main bronchus. Microwave coagulation therapy was performed to excise the lesion and achieve hemostasis. Histopathological analysis confirmed metastatic RCC. The patient was referred for systemic therapy following bronchoscopic intervention. This case highlights the diagnostic challenge of differentiating EM from primary lung cancer, especially in patients with a smoking history and elevated tumor markers. Bronchoscopic microwave coagulation therapy provided a safe and effective method for both diagnosis and airway management. Clinicians should remain vigilant for late recurrence of RCC, even more than a decade after nephrectomy. Bronchoscopic microwave coagulation therapy may serve as a minimally invasive option for the diagnosis and treatment of endobronchial lesions.

CureusVol. 17(11)
Fukuoka Tokushukai Hospital (JP), National Defense Medical College (JP)
Openalex Percentile: Top 48%
Tracheal and airway disorders
AI Navigator

Ask Laika to Summarize, Analyze, and Connect papers live on the map.

Summarize Papers & Methodologies

Extract key findings, datasets, and comparative methods across publications.

Benchmark Rankings & Visual Analytics

Rank top research institutions, authors, funders, topics, and journals by Field-Weighted Citation Impact (FWCI) and paper volume with instant charts.

Connect Distant Disciplines

Bridge topological clusters on the map to find hidden collaborative intersections.