High-Dose Upadacitinib Maintenance Therapy for Refractory Crohn’s Disease: A Case Series and Review of the Literature

This case series illustrates potential benefit and supports the rationale for larger controlled studies evaluating high-dose UPA maintenance therapy.

Authors

R.Z. Kermani
Mohammad Shehab (ORCID: https://orcid.org/0000-0003-2084-3956)
Yousef Alfadhli

Institutions

Mubarak Al Kabeer Hospital (KW)
Kuwait University (KW)
McGill University (CA)

Publication Details

Journal: Case Reports in Gastroenterology
Published: 2025-11-20
DOI: https://doi.org/10.1159/000549674
Primary Topic: Inflammatory Bowel Disease
Type: article
Field-Weighted Citation Impact: 0.00

Controls

|||

ALL TIME

JAN

FEB

MAR

APR

MAY

JUN

JUL

AUG

SEP

OCT

article

High-Dose Upadacitinib Maintenance Therapy for Refractory Crohn’s Disease: A Case Series and Review of the Literature

R.Z. Kermani, Mohammad Shehab, Yousef Alfadhli

Nov 20, 2025

Case Reports in Gastroenterology

Inflammatory Bowel Disease

article

High-Dose Upadacitinib Maintenance Therapy for Refractory Crohn’s Disease: A Case Series and Review of the Literature

R.Z. Kermani, Mohammad Shehab, Yousef Alfadhli

November 20, 2025article en

Abstract

This case series illustrates potential benefit and supports the rationale for larger controlled studies evaluating high-dose UPA maintenance therapy.

Case Reports in GastroenterologyVol. 20(1)

Mubarak Al Kabeer Hospital (KW), Kuwait University (KW), McGill University (CA)

Openalex Percentile: Top 62%

Inflammatory Bowel Disease

DOI Open Access PDF OpenAlex

AI Navigator

Ask Laika to Summarize, Analyze, and Connect papers live on the map.

Summarize Papers & Methodologies

Extract key findings, datasets, and comparative methods across publications.

Benchmark Rankings & Visual Analytics

Rank top research institutions, authors, funders, topics, and journals by Field-Weighted Citation Impact (FWCI) and paper volume with instant charts.

Connect Distant Disciplines

Bridge topological clusters on the map to find hidden collaborative intersections.

High-Dose Upadacitinib Maintenance Therapy for Refractory Crohn’s Disease: A Case Series and Review of the Literature — R.Z. Kermani, Mohammad Shehab, et al. · Case Reports in Gastroenterology (2025) | TGRS Research Map | TGRS