The mineralocorticoid receptor antagonist finerenone enhances cardiovascular recovery upon food intake normalization in obese mice
In the mouse model of HFD-induced obesity and heart failure, finerenone improves weight loss-induced recovery of cardiac function.
Authors
- B. Benjamin (ORCID: https://orcid.org/0000-0002-5853-940X)
- Bruno Fève (ORCID: https://orcid.org/0000-0001-6577-9009)
- Sylvanie Renet
- O. Antoine
- M. Sc. AYA E. ABO SAIDA
- Muriel Paul (ORCID: https://orcid.org/0000-0002-0004-0286)
- N. D. W. Lionel
- Linghui Kong (ORCID: https://orcid.org/0000-0001-7330-3967)
- Vincent Richard (ORCID: https://orcid.org/0000-0002-6961-1753)
- J Frédéric
- Anaïs Dumesnil
- Pierre J. Marie
- Monmirel-Fauconnier Manon
- Frimat Coralie
- Boulkroun Sheerazed
- Ni Dheasmhunaigh Amhrae
Institutions
- Inserm (FR)
- Université Paris Cité (FR)
- Sorbonne Université (FR)
- Centre de Recherche des Cordeliers (FR)
- Normandie Université (FR)
- Paris Cardiovascular Research Center (FR)
- Centre de Recherche Saint-Antoine (FR)
- Université de Rouen Normandie (FR)
Publication Details
- Journal
- Cardiovascular Diabetology
- Published
- 2025-11-24
- DOI
- https://doi.org/10.1186/s12933-025-02935-x
- Primary Topic
- Hormonal Regulation and Hypertension
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Institut National de la Santé et de la Recherche Médicale
- Normandie Université