Development of a highly differentiated rat brain organoid model for exploring glioblastoma invasion dynamics and therapy

The rBOs serve as an effective target brain structure for studying GB invasion parameters and for evaluating therapeutic interventions. Their rapid development into mature brain tissue makes rBOs a valuable brain avatar system for studying tumor-host interactions.

Authors

Institutions

Publication Details

Journal
Neuro-Oncology
Published
2025-11-24
DOI
https://doi.org/10.1093/neuonc/noaf271
Citations
2
Primary Topic
Glioma Diagnosis and Treatment
Type
article
Field-Weighted Citation Impact
3.25

Funders

Controls
|||
ALL TIME
JAN
FEB
MAR
APR
MAY
JUN
JUL
AUG
SEP
OCT
article

Development of a highly differentiated rat brain organoid model for exploring glioblastoma invasion dynamics and therapy

Gunnar Dittmar, Carina Fabian, Wenjing Zhou, Frits Thorsen et al.
2 citations
Neuro-Oncology
Glioma Diagnosis and Treatment
3.25
article

Development of a highly differentiated rat brain organoid model for exploring glioblastoma invasion dynamics and therapy

Gunnar Dittmar, Carina Fabian, Wenjing Zhou, Frits Thorsen, Petr V. Nazarov, Boris Mihaljević, Katharina Sarnow, Magnar Bjørås, Olivier Keunen, Jakub Mieczkowski, Anna Golebiewska, Konrad Grützmann, Yan Li, Saverio Tardito, Barbara Klink, Barbara van Loon, Halala Sdik Saed, Taral R. Lunavat, Simone P. Niclou, Agnieszka Misztak, Hrvoje Miletić, Rolf Bjerkvig, Shannon Sherwin Moreino, Georgia Kanli, Stephanie Schwab, Elena Martínez-García, Mingzhi Han, Zhiyi Xue, Jubayer A. Hossain, J V Joesph, Johannes Meiser, Wenjie Li, Jian Wang, Xingang Li, Yan Zhang, Christian Jaeger, Marzieh Bahador
article en
2 citations

Abstract

The rBOs serve as an effective target brain structure for studying GB invasion parameters and for evaluating therapeutic interventions. Their rapid development into mature brain tissue makes rBOs a valuable brain avatar system for studying tumor-host interactions.

Neuro-Oncology
Boston Children's Hospital (US), Shandong University (CN), Zimmer Biomet (Netherlands) (NL), University of Luxembourg (LU), Norwegian University of Science and Technology (NO), Haukeland University Hospital (NO), Nord University (NO), Comprehensive Cancer Center Vienna (AT), Luxembourg Institute of Health (LU), National Center for Tumor Diseases (DE), Medical Genetics Center (DE), Shandong Provincial Hospital (CN), Norwegian Womens Public Health Association (NO), Qilu Hospital of Shandong University (CN), Shandong First Medical University (CN), University of Bergen (NO), Gdańsk Medical University (PL), University of Split (HR)
National Natural Science Foundation of China, Norges Forskningsråd
Openalex Percentile: Top 7%
Glioma Diagnosis and Treatment
3.25
AI Navigator

Ask Laika to Summarize, Analyze, and Connect papers live on the map.

Summarize Papers & Methodologies

Extract key findings, datasets, and comparative methods across publications.

Benchmark Rankings & Visual Analytics

Rank top research institutions, authors, funders, topics, and journals by Field-Weighted Citation Impact (FWCI) and paper volume with instant charts.

Connect Distant Disciplines

Bridge topological clusters on the map to find hidden collaborative intersections.